B A S E C A R E
Online training丨The 4th China embryo genome project seminar
18th April 2020 · Shandong
On18th April, 2020, the Reproductive Hospital Affiliated to Shandong University successfully held the “4th China embryo genome project seminar”.

China Embryo Genome Project (CEGP) was jointly initiated by the Reproductive Hospital Affiliated to Shandong University and the Genetic Consultation Branch of the Chinese Society of Genetics. Standardization and evaluation of new technologies provide theoretical support for the safety, accuracy and credibility of embryo testing, and ultimately achieve the goal of reducing birth defects and improving the quality of the population. 

On18th April, 2020, the Reproductive Hospital Affiliated to Shandong University successfully held the “4th China embryo genome project seminar”. Affected by the global outbreak of coronavirus epidemic, this seminar was conducted in the form of virtual meeting. Nearly 300 people from127 medical institutions across the country participated in the online discussion.


Academician Chen Zijiang stated in his speech that preventing birth defects is an important task of our current reproductive medicine for improving population quality, population health development strategies and reproductive health. It is also our unshakable responsibility to make China achieve population health and reproductive health at the forefront. Academician Chen Zijiang hopes that colleagues in the Chinese Embryonic Genome Project and friends in the business community will work together to create our own database, our own diagnostic standards, and our own testing methods, truly in line with international standards, and do what they deserve to achieve a healthy China. We contribute, and wish this online seminar a complete success!
Director Gao Yuan said that, there are three major domestic companies have obtained special approval for innovative medical devices for their PGS products and initiated relevant clinical trials. Among them, the PGS kit based on the semiconductor sequencing method has been approved by the State Food and Drug Administration recently. Subsequently, Director Gao conducted a detailed statistical analysis of the relevant data of the PGS clinical trial, and also exchanged and shared the clinical pregnancy data of each group of applicable populations and problems in the application. Subsequently, Director Gao studied PGS clinical trials, chromosomal balanced translocation (including Roche translocation) carrier screening, whether embryo methylation affects the cumulative pregnancy rate of PGS, and the clinical application of other technologies in non-invasive embryo screening in assisted reproduction for Each aspect was elaborated separately. Director Gao also responded online to the questions raised by the participants, and the online interaction was very enthusiastic.
Director Wu Keliang shared the improved blastocyst biopsy method and technical operation points with the experts, and introduced the improved blastocyst biopsy method and quality control program in detail through video. In addition to the explanation of theoretical knowledge, Director Wu also broadcasted different biopsy protocols that need to be used when encountering embryos in different states, and vividly demonstrated the rich biopsy experience of Shandong University, Reproductive centers and to all participating experts. Participants from multiple embryonic laboratories of reproductive centers conducted online consultation and communication with Director Wu on the problems they encountered during the daily embryo biopsy process, and Professor Wu also gave detailed answers one by one.
Director Yan Junhao first made a report on the common problems in the reproductive genetic consultation clinic. Director Yan expressed his views on various situations such as how to consider the age of the woman’s three-generation test-tube babies, how to conduct genetic counseling for certain chromosomal inversion polymorphism patients, and the precautions for genetic counseling for different applicable populations and special circumstances. It also elaborates on specific cases. After the meeting, regarding the genetic counseling of chimeric embryos and the question of whether families carrying certain variant genes with unclear pathogenicity are suitable for PGD, Professor Yan also combined his own practical experience to give detailed answers and questions to the participants. 
This conference received the enthusiastic participation of all the participants. The instructor brought a learning feast to the students through a large number of cases, detailed data and rich clinical practice experience, and answered many clinical questions raised by the students. Everyone is looking forward to having more in-depth communication and exchanges through offline seminars after the epidemic is over, working together to improve the success rate of test-tube babies and prevent birth defects, and help more infertile families. Genetic disease families bring hope!